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about Turkesterone / Ecdysterone Complex

Why Turkesterone / Ecdysterone Complex?

High safety profile!

Doesn’t generally interact with other medications or have any adverse effects that could be potentially dangerous to users even in the higher dosing range (of course assess for tolerance and consult a medical professional in case of side effects).

Non-hormonal!

 

Plant sterols like ecdysterone and turkesterone target the estrogen receptor, not the androgen receptor like anabolic steroids. And work together with a person’s natural hormones without influencing them. In short, they have “steroid-like” effects without the negatives! For example:

    1. Can improve cardiovascular health by lowering cholesterol (potentially through increased conversion of cholesterol to bile acids). As well as through acting like EPO (the endurance drug). Also stimulates the Mas1 receptor which increases vasodilation (improved blood flow) and angiogenesis (formation of new blood vessels).
    2. Can improve liver and kidney function as opposed to harming it like anabolic steroids. It speeds up liver recovery in exposure to toxins and improves glomerular filtration rate (marker of kidney function) in this setting as well (ie protective effects).
    3. Acts as an anti-oxidant in lipids that is more potent than even Vitamin D on a per molecule basis. In this sense it can also slow down oxidative damage and hence prolongs the aging process (more oxidation accelerates cell death).
    4. Anabolic steroids do not act on bone and connective tissue which causes weakening of these structures in relation to muscle. Steroid users are more susceptible to tendon ruptures/tears because their muscle strength exceeds their connective tissue strength. Ecdysteroids increase type 1 Collogen expression dose dependently, promoting joint health. It is osteogenic and prevents bone degeneration through acting on the estrogen receptor in bone tissue as well. It has successfully reversed osteoporosis in mice in medical studies.

Improves glucose metabolism

 

Improves glucose metabolism and is shown to be anti-diabetic and anti-obesogenic. As such, it does not only induce muscle growth and protein synthesis but also prevents excessive weight gain/metabolic syndrome in the process.

 

Has protective effects

 

Has protective effects in neural tissue against toxins. Also stimulates acetylcholinesterase and glutamic decarboxylase, both enzymes that work to promote balance in the nervous system and the brain (ie through GABA production and stopping nervous system excitation due to acetylcholine).

Increases anabolism

 

Increases anabolism in various tissues throughout the body and improves physical performance and induces skeletal muscle growth, even independent of exercise! Turkesterone mainly targets muscle tissue and hence improves muscle mass and body composition, although ecdysterone also has this effect but also exerts it on bone, joint, and even neural tissue as mentioned before. In general, plant sterols’ target tissues vary greatly, which dictates the magnitude of effect seen in those tissues (bone, muscle, joint, cartilage, etc). The combination of a 10% Ajuga Turkestanica extract provides turkesterone and other naturally occurring sterols. Ecdysterone improves the effects seen on muscle tissue but also strengthens bones and connective tissue. This makes it an INCREDIBLE formula for athletes that are constantly pummeling their bodies and joints daily.

Has cosmetic effects

 

A cosmetic effect of plant sterols is that it can also accelerate wound healing and skin regeneration rates when applied topically. Hence if large enough doses are taken over a long enough period it may also serve to improve skin health if enough of the active compounds reach and build up in skin cells. It does this by promoting keratinocyte differentiation.

Provides 750mg of sterol extracts

 

Toxicity is seen at some 6-9grams/kg bodyweight and benefits are seen at around 10mg/kg. Hence the lowest effective dose for an 80kg individual is 800mg of sterols. Gram doses have been taken by users without any side effects noted (anecdotal). The Turkesterone/Ecdysterone Complex provides 750mg of sterol extracts PER CAPSULE! A serving will provide double this!

Has low-solubility compounds

Plant sterols are fat soluble so should be consumed with a meal, however, it can also be taken on an empty stomach if tolerated due to the addition of black pepper extract. Black pepper extract or bioperine or any other similar formulations slow down the gut and allow time for low-solubility compounds like Turkesterone and Ecdysterone to absorb in the gastrointestinal tract independent of fat. Addition of this guarantees optimal utilization of the ingredients in the formula.

High safety profile!

Doesn’t generally interact with other medications or have any adverse effects that could be potentially dangerous to users even in the higher dosing range (of course assess for tolerance and consult a medical professional in case of side effects).

Non-hormonal!

Doesn’t generally interact with other medications or have any adverse effects that could be potentially dangerous to users even in the higher dosing range (of course assess for tolerance and consult a medical professional in case of side effects).

Improves glucose metabolism

Improves glucose metabolism and is shown to be anti-diabetic and anti-obesogenic. As such, it does not only induce muscle growth and protein synthesis but also prevents excessive weight gain/metabolic syndrome in the process.

Has Protective Effects

Has protective effects in neural tissue against toxins. Also stimulates acetylcholinesterase and glutamic decarboxylase, both enzymes that work to promote balance in the nervous system and the brain (ie through GABA production and stopping nervous system excitation due to acetylcholine).

Increases anabolism

Increases anabolism in various tissues throughout the body and improves physical performance and induces skeletal muscle growth, even independent of exercise! Turkesterone mainly targets muscle tissue and hence improves muscle mass and body composition, although ecdysterone also has this effect but also exerts it on bone, joint, and even neural tissue as mentioned before. In general, plant sterols’ target tissues vary greatly, which dictates the magnitude of effect seen in those tissues (bone, muscle, joint, cartilage, etc). The combination of a 10% Ajuga Turkestanica extract provides turkesterone and other naturally occurring sterols. Ecdysterone improves the effects seen on muscle tissue but also strengthens bones and connective tissue. This makes it an INCREDIBLE formula for athletes that are constantly pummeling their bodies and joints daily.

Has cosmetic effects

A cosmetic effect of plant sterols is that it can also accelerate wound healing and skin regeneration rates when applied topically. Hence if large enough doses are taken over a long enough period it may also serve to improve skin health if enough of the active compounds reach and build up in skin cells. It does this by promoting keratinocyte differentiation.

Provides 750mg of sterol extracts

Toxicity is seen at some 6-9grams/kg bodyweight and benefits are seen at around 10mg/kg. Hence the lowest effective dose for an 80kg individual is 800mg of sterols. Gram doses have been taken by users without any side effects noted (anecdotal). The Turkesterone/Ecdysterone Complex provides 750mg of sterol extracts PER CAPSULE! A serving will provide double this!

Has low-solubility compounds

Plant sterols are fat soluble so should be consumed with a meal, however, it can also be taken on an empty stomach if tolerated due to the addition of black pepper extract. Black pepper extract or bioperine or any other similar formulations slow down the gut and allow time for low-solubility compounds like Turkesterone and Ecdysterone to absorb in the gastrointestinal tract independent of fat. Addition of this guarantees optimal utilization of the ingredients in the formula.

Citations:

Patel, K. (2020, November 20). ECDYSTEROIDS supplement – health benefits, dosage, side effects. Examine.com. Retrieved May 27, 2022, from https://examine.com/supplements/ecdysteroids/

 

Syrov VN, Nasyrova SS, Khushbaktova ZA. [The results of experimental study of phytoecdysteroids as erythropoiesis stimulators in laboratory animals]. Eksp Klin Farmakol. 1997 May-Jun;60(3):41-4. Russian. PMID: 9324397.

 

Dinan L, Dioh W, Veillet S, Lafont R. 20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases. Biomedicines. 2021 Apr 29;9(5):492. doi: 10.3390/biomedicines9050492. PMID: 33947076; PMCID: PMC8146789.